Ingredient comparison

Palmitoyl Tripeptide-1 vs Retinyl Palmitate: which one is right for your skin?

Same comparison whichever way you searched it: Retinyl Palmitate vs Palmitoyl Tripeptide-1.

Short answer: Honestly, either one works. Choose by your skin type and what your routine already has. If you are pregnant, Palmitoyl Tripeptide-1 is the safer one to reach for.

Chemical structure of Palmitoyl Tripeptide-1 (Palmitoyl Tripeptide-1)Palmitoyl Tripeptide-1Decent support
Chemical structure of Retinyl Palmitate (Retinyl Palmitate)Retinyl PalmitateDecent support
6
Efficacy
6
2
Hydration
1
3
Barrier
0
1
Brightening
2
0
Acne
1
6
Anti-aging
5
Palmitoyl Tripeptide-1 versus Retinyl Palmitate, compared
ComparedPalmitoyl Tripeptide-1Retinyl Palmitate
PotencySimilarSimilar
Evidencemoderate evidencemoderate evidence
Irritation riskLowLow
Clogs poresLowLow
In pregnancyConsidered safeNot in pregnancy
On a labelusually effective at 0.0003-0.003%works best above 0.3%

So which should you pick?

Choose Palmitoyl Tripeptide-1 if

  • you are pregnant or breastfeeding, since only Palmitoyl Tripeptide-1 is considered safe

The honest bottom line: Honestly, either one works. Choose by your skin type and what your routine already has. If you are pregnant, Palmitoyl Tripeptide-1 is the safer one to reach for.

Pregnancy: Only Palmitoyl Tripeptide-1 is considered safe to use in pregnancy.

No known clash between these two. If you want both, you can layer them; introduce one at a time.

Check these two in the tool →Or decode a whole product label →

From our dataNeither has to be the answer: 58 other ingredients in our glossary share a family with these two.

Palmitoyl Tripeptide-1 vs Retinyl Palmitate, answered

Which is stronger, Palmitoyl Tripeptide-1 or Retinyl Palmitate?

They are close in strength: Palmitoyl Tripeptide-1 and Retinyl Palmitate score similarly on efficacy. Choose by skin type rather than power.

Is Palmitoyl Tripeptide-1 or Retinyl Palmitate better for sensitive skin?

Both carry a similar irritation risk (low). Patch test either one before using it daily.

Can you use Palmitoyl Tripeptide-1 and Retinyl Palmitate together?

There is no known clash between them. You can layer them if you like, just introduce one at a time.

General guidance, not medical advice. Read the full pages on Palmitoyl Tripeptide-1 and Retinyl Palmitate.