The Ordinary Retinol 0.5% in Squalane

Serum~€8typical, July 2026

Our read, in one look

Retinol is the reason to consider this serum, with Squalane behind it.

The case for it

  • Retinol, strong evidence for lines and firmness
  • Squalane, strong evidence for the barrier
  • No fragrance, alcohol, silicones or parabens

Mind this

  • Avoid in pregnancy: Retinol
  • Evenings only, sunscreen the next morning
  • Retinol: sits high on irritation, so ease it in
Best for normal, oily, combo, dry skinFind it on amazon.com
Maya's read

The Ordinary Retinol 0.5% in Squalane is a serum built around Retinol, Squalane and Jojoba Oil. It leans strongest on barrier repair, anti-aging. Best suited to normal, oily and combo skin. One caveat: it's best skipped during pregnancy.

Skip it if you're pregnant or breastfeeding: it contains retinol, best paused until after.

What it delivers

Hydration4
Barrier repair7
Brightening / tone4
Oil-control & blemishes3
Anti-aging9

How it feels A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film. (estimated from the formula)

What's in it that matters

The molecule doing the workRetinolHero Active · strong evidence

Gold-standard over-the-counter retinoid with strong anti-aging data; can easily irritate and requires careful introduction and good barrier support.

  • SqualaneEmollientstrong evidence

    Stable, lightweight emollient that mimics skin’s natural lipids and supports barrier without heavy greasiness for most skin types.

  • Jojoba OilEmollientstrong evidence

    Liquid wax ester closely resembling human sebum that helps balance oil, soften skin and support barrier without heavy greasiness for most.

  • Caprylic/Capric TriglycerideEmollientstrong evidence

    Light emollient ester that improves slip and reduces transepidermal water loss; may be problematic for some fungal-acne-prone users.

How to use it

Night only. Start 2–3 nights a week and build up as your skin adjusts, and always wear sunscreen the next morning, because retinoids make skin more sun-sensitive.

Keep it away from

  • Exfoliating acids (AHA / BHA)
  • Benzoyl peroxide
  • Strong vitamin C (L-ascorbic acid)
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Where it acts

The same cross-section as our 500 dalton page, with this formula's actives on the layer each one works on. Depth is the anatomy's, never an ingredient's.

4 of this product's actives have a layer we can defend.

Sources for the sourced ones: Szymanski et al. 2020: retinoic acid and its derivatives in skin.

Against the average serum

HydrationBarrier repairBrighteningOil-controlAnti-aging
This productMedian serum (27 in catalogue)

It scores higher than the median serum on anti-aging.

It gives up ground on hydration and brightening.

A median, not an average: one unusual formula should not move the middle. The numbers are the same 0 to 10 reads the comparison pages use.

The full ingredients list, decoded

Every ingredient on the label, in the order it appears (highest amount first). We link the 7 our library knows, name what each one does, and flag anything that can irritate or clog. The rest we leave plain, nothing is hidden.

All 8 ingredients, decoded
  1. SqualaneEmollient
  2. RetinolRetinoid
    pregnancy: avoidcan irritate
  3. Solanum Lycopersicum (Tomato) Fruit ExtractBotanical extract
  4. mild irritant
  5. BHTAntioxidant
    mild irritant
Copy the raw INCI list

Squalane, Caprylic/Capric Triglyceride, Simmondsia Chinensis (Jojoba) Seed Oil, Retinol, Solanum Lycopersicum (Tomato) Fruit Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Hydroxymethoxyphenyl Decanone, BHT

Read enough? Find it on amazon.com

We don't make or sell skincare of our own. So there's nothing here we're trying to push, just an honest read of whether this formula suits your skin.

Compare it with…

All 17 comparisons

Decode your product

Photograph the front and the ingredients list on the back. We check every product against the same knowledge base by hand, so this takes days, not seconds.

The photos

Common questions

Is The Ordinary Retinol 0.5% in Squalane good for normal skin?

By our read of the formula, it suits normal, oily, combo skin. The Ordinary Retinol 0.5% in Squalane is a serum built around Retinol, Squalane and Jojoba Oil. It leans strongest on barrier repair, anti-aging. Best suited to normal, oily and combo skin. One caveat: it's best skipped during pregnancy.

How do you use The Ordinary Retinol 0.5% in Squalane?

Night only. Start 2–3 nights a week and build up as your skin adjusts, and always wear sunscreen the next morning, because retinoids make skin more sun-sensitive.

What are the key ingredients in The Ordinary Retinol 0.5% in Squalane?

The actives that do the work are Retinol, Squalane, Jojoba Oil, Caprylic/Capric Triglyceride. The rest of the list is texture, preservatives and emulsifiers that hold the formula together.

Is The Ordinary Retinol 0.5% in Squalane safe during pregnancy?

Avoid in pregnancy: Retinol. When in doubt, check with your doctor before using it.

What the 3D scene shows

The scene shows The Ordinary Retinol 0.5% in Squalane beside a cross-section of skin, with 2 of its ingredients drawn at the layer each one acts on and at one shared molecular scale: Squalane in the stratum corneum, the dead outer layer where most skincare works; Retinol in the living epidermis, among the cells that are still dividing. Depths come from the same sourced layer data as the rest of this site, and any ingredient whose layer is not established is left out rather than guessed.

The Ordinary prints: 0.5% retinol. Read on the brand's own product page, 2026-08-10.

Building the scene…

This is skin, in section.

The molecules floating inside it are from this bottle, each at the layer it works on, drawn to one true scale. Drag to turn, pinch or scroll to zoom, tap a molecule for its evidence.

Skin in section· molecules from this formula · one true scale
tap it to decode ↻
Retinol 0.5% in SqualaneThe Ordinary · Serum · ~€8

Retinol is the reason to consider this serum, with Squalane behind it.

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