Ingredient glossary

Licochalcone A

What Licochalcone A does for your skin, who it suits, and what to watch for.

INCI: Glycyrrhiza Inflata Root Extract · Also: Licorice Extract

Decent support

In short: Licochalcone A delivers anti inflammatory and antioxidant, suits most skin types, and the evidence behind it is moderate.

What it does
Anti inflammatory, antioxidant
Best for
Most skin types
Evidence
Moderate
How long
Never measured
Does it clash with what you use? Check it →

The Glow take

The kind of ingredient sensitive skin quietly loves.

Licochalcone A earns its place by calming things down: less redness, less sting, a happier barrier. Not a headline active.

— Maya

What it does

  • anti inflammatory
  • antioxidant
  • brightening

moderate evidenceControlled studies show reduced redness and irritation. Tone benefits are mostly measured alongside stronger brighteners rather than for this extract on its own.

Who it's for, and who should skip it

Tends to suit

  • sensitive
  • pigmentation
  • rosacea
  • all

Approach with care

No specific group flagged to avoid it.

  • Clogs poresLow
  • Irritation riskLow

How it fits each skin type

  • DrySuits
  • CombinationSuits
  • OilySuits
  • SensitiveSuits

Often chosen for pigmentation, rosacea.

Where it fits in your routine

WhenMorning
Where in the orderAfter cleansing, under your SPF

Nobody has published how long this takes to work.

What is known, and what is missing

Measured on: facial erythema - instrumental redness (a*) or investigator-graded.

What is known: licochalcone A is the anti-inflammatory fraction of Glycyrrhiza inflata, manufacturer-run human work reports that formulations containing it reduce experimentally provoked erythema within a day or two, and an eight-week study of a licochalcone A skincare regimen in people with red facial skin reported less redness. What is missing is a vehicle-controlled trial of the extract itself with interim visits: the erythema work is an experimental challenge model rather than clinical redness over time, and the regimen study tests a whole product range without a comparator. The base's brightening 5 is likewise measured alongside stronger brighteners, so neither of its two jobs has a published onset.

Manufacturer-run human erythema-model studies of licochalcone A and the regimen study in red facial skin described in the base row; no vehicle-controlled trial of the extract identified.

Plays well with

Licochalcone A, answered

Is Licochalcone A safe during pregnancy?

Yes. Licochalcone A is considered safe to use during pregnancy and breastfeeding. As with anything, if you are unsure it is worth a quick word with your doctor or midwife.

Who should avoid Licochalcone A?

No specific group is flagged to avoid Licochalcone A. It is well tolerated by most skin. Still, introduce anything new one product at a time.

What concentration of Licochalcone A actually works?

Its concentration is rarely printed on the label, so use the ingredient list as your clue: near the top third it is likely doing real work, near the bottom it is more of a sprinkle.

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Sources & how we reviewed this

Last reviewed August 2026. Educational information about a cosmetic ingredient, not medical advice.