Head to head
Anua Niacinamide 10% + TXA 4% Serum vs Medik8 Crystal Retinal 6
Same comparison whichever way you searched it: Medik8 Crystal Retinal 6 vs Anua Niacinamide 10% + TXA 4% Serum.
The bottom lineAnua Niacinamide 10% + TXA 4% Serum and Medik8 Crystal Retinal 6 are close on what they deliver, so it comes down to your skin: Anua Niacinamide 10% + TXA 4% Serum is the kinder pick for sensitive or reactive skin since it is fragrance-free.
Anua Niacinamide 10% + TXA 4% Serum keeps clear of pregnancy-flagged actives, while Medik8 Crystal Retinal 6 carries one that is best paused in pregnancy.
Which should you pick?
Pick Niacinamide 10% + TXA 4% Serum if
- you are dealing with breakouts and oiliness
- your barrier feels stressed and needs the support
- your skin is sensitive or reacts to fragrance
Pick Crystal Retinal 6 if
- fine lines and firmness are the goal
What each delivers
Side by side
| Niacinamide 10% + TXA 4% Serum | Crystal Retinal 6 | |
|---|---|---|
| Type | Serum | Serum |
| Key actives | Glycerin, Niacinamide 10%, Ceramide 3 | Glycerin, Retinal, Squalane |
| Texture | A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film. | A rich, cushiony cream that sinks in slowly. |
| Fragrance | None detected | Contains fragrance |
| Fungal-acne safe | Not likely | Not likely |
| Pregnancy | No flagged actives | One caution |
| Ingredients | 51 listed | 47 listed |
| Price | ~€20 | ~€86 |
What's in one but not the other
Only in Niacinamide 10% + TXA 4% Serum
Both share
Only in Crystal Retinal 6
The molecule doing the work
Better for…
- Dark spots & uneven toneEither works
- Fine lines & firmnessCrystal Retinal 6
- Breakouts & congestionNiacinamide 10% + TXA 4% Serum
- Dryness & dehydrationEither works
- Sensitive, reactive skinNiacinamide 10% + TXA 4% Serum
Anua Niacinamide 10% + TXA 4% Serum is the cheaper of the two (~€20 vs ~€86).
Ready to pick one?
Affiliate links, so a purchase sends us a small commission at no extra cost to you. As an Amazon Associate, Glow Simplified earns from qualifying purchases. We make and sell nothing here, so the verdict above never bends toward a sale.
Common questions
Is Anua Niacinamide 10% + TXA 4% Serum or Medik8 Crystal Retinal 6 better for fine lines & firmness?
For fine lines & firmness, Medik8 Crystal Retinal 6 is the stronger pick by our read of the two formulas. Anua Niacinamide 10% + TXA 4% Serum and Medik8 Crystal Retinal 6 are close on what they deliver, so it comes down to your skin: Anua Niacinamide 10% + TXA 4% Serum is the kinder pick for sensitive or reactive skin since it is fragrance-free. Anua Niacinamide 10% + TXA 4% Serum keeps clear of pregnancy-flagged actives, while Medik8 Crystal Retinal 6 carries one that is best paused in pregnancy.
Which is cheaper, Anua Niacinamide 10% + TXA 4% Serum or Medik8 Crystal Retinal 6?
Anua Niacinamide 10% + TXA 4% Serum is the cheaper of the two (~€20 vs ~€86).
Can I use Anua Niacinamide 10% + TXA 4% Serum and Medik8 Crystal Retinal 6 together?
They are both serums, so you would normally pick one rather than layer both in the same step. You can keep both and alternate them (morning and night, or on different days) if you like variety, but you do not need two.
Compare it with…
All 33 comparisons
- Niacinamide 10% + TXA 4% Serum vs The Ordinary Niacinamide 10% + Zinc 1%
- Niacinamide 10% + TXA 4% Serum vs The Ordinary Hyaluronic Acid 2% + B5 (Original Formulation)
- Niacinamide 10% + TXA 4% Serum vs The Ordinary Hyaluronic Acid 2% + B5 (with Ceramides)
- Niacinamide 10% + TXA 4% Serum vs CeraVe Resurfacing Retinol Serum
- Niacinamide 10% + TXA 4% Serum vs The Ordinary Azelaic Acid Suspension 10%
- Niacinamide 10% + TXA 4% Serum vs La Roche-Posay Hyalu B5 Suractivated Serum
- Niacinamide 10% + TXA 4% Serum vs Eucerin Anti-Pigment Dual Serum
- Niacinamide 10% + TXA 4% Serum vs The Ordinary Caffeine Solution 5% + EGCG Eye Serum
- Niacinamide 10% + TXA 4% Serum vs The Ordinary Multi-Peptide + HA Serum
- Niacinamide 10% + TXA 4% Serum vs Celimax The Vita A Retinal Shot Tightening Booster
- Niacinamide 10% + TXA 4% Serum vs Vichy Minéral 89 Hyaluronic Acid Booster
- Crystal Retinal 6 vs The Ordinary Niacinamide 10% + Zinc 1%
- Crystal Retinal 6 vs The Ordinary Hyaluronic Acid 2% + B5 (Original Formulation)
- Crystal Retinal 6 vs The Ordinary Hyaluronic Acid 2% + B5 (with Ceramides)
- Crystal Retinal 6 vs The Ordinary Vitamin C Suspension 23% + HA Spheres 2%
- Crystal Retinal 6 vs The Ordinary Retinol 0.5% in Squalane
- Crystal Retinal 6 vs CeraVe Resurfacing Retinol Serum
- Crystal Retinal 6 vs The Ordinary Azelaic Acid Suspension 10%
- Crystal Retinal 6 vs La Roche-Posay Hyalu B5 Suractivated Serum
- Crystal Retinal 6 vs Eucerin Anti-Pigment Dual Serum
- Crystal Retinal 6 vs The Ordinary Caffeine Solution 5% + EGCG Eye Serum
- Crystal Retinal 6 vs The Ordinary Multi-Peptide + HA Serum
- Crystal Retinal 6 vs The Ordinary Granactive Retinoid 2% Emulsion
- Crystal Retinal 6 vs The Ordinary Granactive Retinoid 5% in Squalane
- Crystal Retinal 6 vs Geek & Gorgeous A-Game 10
- Crystal Retinal 6 vs Celimax The Vita A Retinal Shot Tightening Booster
- Crystal Retinal 6 vs Medicube PDRN Pink Peptide Serum
- Crystal Retinal 6 vs Medik8 Liquid Peptides
- Crystal Retinal 6 vs Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum
- Crystal Retinal 6 vs Beauty of Joseon Glow Deep Serum
- Crystal Retinal 6 vs iUNIK Beta Glucan Power Moisture Serum
- Crystal Retinal 6 vs The Ordinary GF 15% Solution
- Crystal Retinal 6 vs Vichy Minéral 89 Hyaluronic Acid Booster