Head to head
La Roche-Posay Hyalu B5 Suractivated Serum vs Medicube PDRN Pink Peptide Serum
Same comparison whichever way you searched it: Medicube PDRN Pink Peptide Serum vs La Roche-Posay Hyalu B5 Suractivated Serum.
The bottom lineLa Roche-Posay Hyalu B5 Suractivated Serum and Medicube PDRN Pink Peptide Serum land in much the same place on performance, so value decides it: Medicube PDRN Pink Peptide Serum does the same job for less.
Answer nine questions and the app picks between them for your skin.
Cost per use
$0.27 an applicationabout 150 uses from 30 ml
a usual amount, not a measured dose: 3-5 drops, about 0.2 ml; from $40 as read in September 2026 and a 30 ml pack.
how this is counted
About $0.27 an application, about 150 uses from 30 ml.
- a convention: no trial has measured a serum dose
- Measured or assumed: the rule, and the dose table
€0.20 an applicationabout 150 uses from 30 ml
a usual amount, not a measured dose: 3-5 drops, about 0.2 ml; from €30 as read in September 2026 and a 30 ml pack.
how this is counted
About €0.20 an application, about 150 uses from 30 ml.
- a convention: no trial has measured a serum dose
- Measured or assumed: the rule, and the dose table
Per application, Medicube PDRN Pink Peptide Serum is the cheaper: €0.20 against $0.27.
Which should you pick?
Pick Hyalu B5 Suractivated Serum if
- your breakouts are the fungal kind (Malassezia): nothing on its label was measured to feed the yeast
Pick PDRN Pink Peptide Serum if
- you are dealing with breakouts and oiliness
- you want the more affordable option
What each delivers
Side by side
| Hyalu B5 Suractivated Serum | PDRN Pink Peptide Serum | |
|---|---|---|
| Type | Serum | Serum |
| Key actives | Glycerin, Pro-vitamin B5, Hyaluronic acid | Niacinamide, Glycerin, Hyaluronic acid |
| Texture | A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film. | A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film. |
| Fragrance | Contains fragrance | Contains fragrance |
| Feeds Malassezia | none measured / none inferred | 1 measured / none inferred |
| Pregnancy | No flagged actives | No flagged actives |
| Ingredients | 32 listed | 40 listed |
| Price | ~$40 | ~€30 |
What's in one but not the other
The two labels share 6 of the 66 ingredients between them. The actives are where they part company.
What each one adds acts on The stratum corneum, The living epidermis, Not established for La Roche-Posay Hyalu B5 Suractivated Serum and The living epidermis, Not established for Medicube PDRN Pink Peptide Serum. That is the layer each is understood to act on, not how deep it travels.
Only in La Roche-Posay Hyalu B5 Suractivated Serum
Only in Medicube PDRN Pink Peptide Serum
Medicube PDRN Pink Peptide Serum is a different bottle only for: niacinamide, pdrn, ghk-cu, palmitoyl pentapeptide-4.
The molecule doing the work
Better for…
- Dark spots & uneven toneEither works
- Fine lines & firmnessEither works
- Breakouts & congestionPDRN Pink Peptide Serum
- Dryness & dehydrationEither works
- Sensitive, reactive skinHyalu B5 Suractivated Serum
Who each suits
- La Roche-Posay Hyalu B5 Suractivated Serum
- dry, sensitive, normal
- Medicube PDRN Pink Peptide Serum
- dry, combination, normal · avoid with breastfeeding, fish allergy, pregnancy and very sensitive skin (at high strength)
Medicube PDRN Pink Peptide Serum is the cheaper of the two (~€30 vs ~$40).
Ready to pick one?
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Common questions
Is La Roche-Posay Hyalu B5 Suractivated Serum or Medicube PDRN Pink Peptide Serum better for breakouts & congestion?
For breakouts & congestion, Medicube PDRN Pink Peptide Serum is the stronger pick by our read of the two formulas. La Roche-Posay Hyalu B5 Suractivated Serum and Medicube PDRN Pink Peptide Serum land in much the same place on performance, so value decides it: Medicube PDRN Pink Peptide Serum does the same job for less.
Which is cheaper, La Roche-Posay Hyalu B5 Suractivated Serum or Medicube PDRN Pink Peptide Serum?
Medicube PDRN Pink Peptide Serum is the cheaper of the two (~€30 vs ~$40).
Can I use La Roche-Posay Hyalu B5 Suractivated Serum and Medicube PDRN Pink Peptide Serum together?
They are both serums, so you would normally pick one rather than layer both in the same step. You can keep both and alternate them (morning and night, or on different days) if you like variety, but you do not need two.
What the scene shows
The cross-section at the top of this page is not decoration and not a diagram of the skin in general: it places the molecules these two are sold on at the layer each is understood to act on. La Roche-Posay Hyalu B5 Suractivated Serum is placed by Glycerin (the stratum corneum), Pro-vitamin B5 (the stratum corneum), Hyaluronic acid (the stratum corneum). Medicube PDRN Pink Peptide Serum is placed by Niacinamide (the living epidermis), Glycerin (the stratum corneum), Hyaluronic acid (the stratum corneum). A layer is where an ingredient does its work, never how deep it travels, and never a claim about how well it works.
Compare it with…
46 duels are built for this serum, The Ordinary Hyaluronic Acid 2% + B5 (Original Formulation) and CeraVe Resurfacing Retinol Serum among them: type a name, or pick one below.