Head to head
La Roche-Posay Hyalu B5 Suractivated Serum vs The Ordinary Multi-Peptide + HA Serum
Same comparison whichever way you searched it: The Ordinary Multi-Peptide + HA Serum vs La Roche-Posay Hyalu B5 Suractivated Serum.
The bottom lineLa Roche-Posay Hyalu B5 Suractivated Serum and The Ordinary Multi-Peptide + HA Serum are close on what they deliver, so it comes down to your skin: The Ordinary Multi-Peptide + HA Serum is the kinder pick for sensitive or reactive skin since it is fragrance-free.
Answer nine questions and the app picks between them for your skin.
Cost per use
$0.27 an applicationabout 150 uses from 30 ml
a usual amount, not a measured dose: 3-5 drops, about 0.2 ml; from $40 as read in September 2026 and a 30 ml pack.
how this is counted
About $0.27 an application, about 150 uses from 30 ml.
- a convention: no trial has measured a serum dose
- Measured or assumed: the rule, and the dose table
€0.14 an applicationabout 150 uses from 30 ml
a usual amount, not a measured dose: 3-5 drops, about 0.2 ml; from €21 as read in September 2026 and a 30 ml pack.
how this is counted
About €0.14 an application, about 150 uses from 30 ml.
- a convention: no trial has measured a serum dose
- Measured or assumed: the rule, and the dose table
Per application, The Ordinary Multi-Peptide + HA Serum is the cheaper: €0.14 against $0.27.
Which should you pick?
Pick Hyalu B5 Suractivated Serum if
- dark spots, dullness or an uneven tone are your focus
- your breakouts are the fungal kind (Malassezia): nothing on its label was measured to feed the yeast
Pick Multi-Peptide + HA Serum if
- your skin is sensitive or reacts to fragrance
- you want the more affordable option
What each delivers
Side by side
| Hyalu B5 Suractivated Serum | Multi-Peptide + HA Serum | |
|---|---|---|
| Type | Serum | Serum |
| Key actives | Glycerin, Pro-vitamin B5, Hyaluronic acid | Glycerin, Crosslinked sodium HA, Hyaluronic acid |
| Texture | A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film. | A light, fast-absorbing texture that layers cleanly under the rest of your routine, with no greasy film. |
| Fragrance | Contains fragrance | None detected |
| Feeds Malassezia | none measured / none inferred | 2 measured / none inferred |
| Pregnancy | No flagged actives | No flagged actives |
| Ingredients | 32 listed | 51 listed |
| Price | ~$40 | ~€21 |
What's in one but not the other
The two labels share 9 of the 74 ingredients between them. The actives are where they part company.
What each one adds acts on The stratum corneum, The living epidermis, Not established for La Roche-Posay Hyalu B5 Suractivated Serum and The stratum corneum, Not established for The Ordinary Multi-Peptide + HA Serum. That is the layer each is understood to act on, not how deep it travels.
Only in La Roche-Posay Hyalu B5 Suractivated Serum
Only in The Ordinary Multi-Peptide + HA Serum
The Ordinary Multi-Peptide + HA Serum is a different bottle only for: crosslinked sodium ha, urea, sodium pca, allantoin.
Where each label stops telling you the dose
Ingredients are listed in order of how much is inside, but only down to 1%. Below that the brand may list them in any order it likes, so the bottom of a label is a set, not a ranking. These two stop being a ranking in very different places.
La Roche-Posay Hyalu B5 Suractivated Serum
ordered for its first 81%
- 1Aqua/Water/Eau
- 2Glycerin
- 3Alcohol Denat
- 4Propylene Glycol
- 5Panthenol
- 6Pentylene Glycol
- 7Dimethicone
- 8PEG-6 Caprylic/Capric Glycerides
- 9Alpinia Galanga Leaf Extract
- 10Calcium Chloride
- 11Glyceryl Isostearate
- 12Madecassoside
- 13PPG-6-Decyltetradeceth-30
- 14Sodium Acetylated Hyaluronate
- 15Sodium Hyaluronate
- 16Algin
- 17Adenosine
- 18Ammonium Polyacryloyldimethyl Taurate
- 19Propanediol
- 20Hydrolyzed Hyaluronic Acid
- 21Hydroxyacetophenone
- 22Caprylic/Capric Triglyceride
- 23Caprylyl Glycol
- 24Citric Acid
- 25Trisodium Ethylenediamine Disuccinate
- 26Acetyl Glucosamine
- 27Xanthan Gum
- 28Butylene Glycol
- 291,2-Hexanediol
- 30Tocopherol
- 31Phenoxyethanol
- 32Parfum/Fragrance
6 of 32 sit below the line, marked by Xanthan Gum.
The Ordinary Multi-Peptide + HA Serum
ordered for its first 76%
- 1Aqua (Water)
- 2Glycerin
- 3Lactococcus Ferment Lysate
- 4Acetyl Hexapeptide-8
- 5Pentapeptide-18
- 6Palmitoyl Tripeptide-1
- 7Palmitoyl Tetrapeptide-7
- 8Palmitoyl Tripeptide-38
- 9Dipeptide Diaminobutyroyl Benzylamide Diacetate
- 10Acetylarginyltryptophyl Diphenylglycine
- 11Sodium Hyaluronate Crosspolymer
- 12Sodium Hyaluronate
- 13Allantoin
- 14Glycine
- 15Alanine
- 16Serine
- 17Valine
- 18Isoleucine
- 19Proline
- 20Threonine
- 21Histidine
- 22Phenylalanine
- 23Arginine
- 24Aspartic Acid
- 25Trehalose
- 26Fructose
- 27Glucose
- 28Maltose
- 29Urea
- 30Sodium PCA
- 31PCA
- 32Sodium Lactate
- 33Citric Acid
- 34Hydroxypropyl Cyclodextrin
- 35Sodium Chloride
- 36Sodium Hydroxide
- 37Butylene Glycol
- 38Pentylene Glycol
- 39Acacia Senegal Gum
- 40Xanthan Gum
- 41Carbomer
- 42Polysorbate 20
- 43PPG-26-Buteth-26
- 44PEG-40 Hydrogenated Castor Oil
- 45Trisodium Ethylenediamine Disuccinate
- 46Ethoxydiglycol
- 47Sodium Benzoate
- 48Caprylyl Glycol
- 49Ethylhexylglycerin
- 50Phenoxyethanol
- 51Chlorphenesin
12 of 51 sit below the line, marked by Xanthan Gum.
Below the line is not too little to work: ceramides, retinoids and peptides all act far under a percent. It means the position stops carrying information. Where the line falls is inferred from the first ingredient whose whole job is done at a fraction of a percent, so it is a close read of the label rather than a number from the formula sheet.
The molecule doing the work
Better for…
- Dark spots & uneven toneHyalu B5 Suractivated Serum
- Dryness & dehydrationEither works
- Sensitive, reactive skinMulti-Peptide + HA Serum
Who each suits
- La Roche-Posay Hyalu B5 Suractivated Serum
- dry, sensitive, normal
- The Ordinary Multi-Peptide + HA Serum
- dry, sensitive, normal · avoid with very sensitive skin (at high strength)
The Ordinary Multi-Peptide + HA Serum is the cheaper of the two (~€21 vs ~$40).
Ready to pick one?
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Common questions
Is La Roche-Posay Hyalu B5 Suractivated Serum or The Ordinary Multi-Peptide + HA Serum better for dark spots & uneven tone?
For dark spots & uneven tone, La Roche-Posay Hyalu B5 Suractivated Serum is the stronger pick by our read of the two formulas. La Roche-Posay Hyalu B5 Suractivated Serum and The Ordinary Multi-Peptide + HA Serum are close on what they deliver, so it comes down to your skin: The Ordinary Multi-Peptide + HA Serum is the kinder pick for sensitive or reactive skin since it is fragrance-free.
Which is cheaper, La Roche-Posay Hyalu B5 Suractivated Serum or The Ordinary Multi-Peptide + HA Serum?
The Ordinary Multi-Peptide + HA Serum is the cheaper of the two (~€21 vs ~$40).
Can I use La Roche-Posay Hyalu B5 Suractivated Serum and The Ordinary Multi-Peptide + HA Serum together?
They are both serums, so you would normally pick one rather than layer both in the same step. You can keep both and alternate them (morning and night, or on different days) if you like variety, but you do not need two.
What the scene shows
The cross-section at the top of this page is not decoration and not a diagram of the skin in general: it places the molecules these two are sold on at the layer each is understood to act on. La Roche-Posay Hyalu B5 Suractivated Serum is placed by Glycerin (the stratum corneum), Pro-vitamin B5 (the stratum corneum), Hyaluronic acid (the stratum corneum). The Ordinary Multi-Peptide + HA Serum is placed by Glycerin (the stratum corneum), Crosslinked sodium HA (the stratum corneum), Hyaluronic acid (the stratum corneum). A layer is where an ingredient does its work, never how deep it travels, and never a claim about how well it works.
Compare it with…
54 duels are built for this serum, The Ordinary Hyaluronic Acid 2% + B5 (Original Formulation) and The Ordinary Hyaluronic Acid 2% + B5 (Original Formulation) among them: type a name, or pick one below.